ACOSTIN 1MIU INJECTION

Uses and Benefits of ACOSTIN 1MIU INJECTION (COLISTIMETHATE SODIUM 1000000 IU)

Colistimethate Sodium is used to treat serious bacterial infections, especially those caused by multi-drug resistant organisms, when other antibiotics are not effective.

WHAT THIS MEDICINE IS USED FOR

• Serious infections of the lungs, blood, or urinary tract caused by resistant gram-negative bacteria
• Hospital-acquired infections, including those in intensive care units
• Infections in patients with cystic fibrosis (as inhalation therapy in some cases)
• Used when other antibiotics have failed or are not suitable

HOW IT WORKS

• It works by binding to the outer membrane of certain bacteria
• This disrupts the bacterial cell membrane, causing the bacteria to die
• It is effective mainly against gram-negative bacteria

WHAT IT IS NOT USED FOR

• Viral infections such as cold, flu, or COVID-19
• Fungal infections
• Infections caused by bacteria not sensitive to this medicine
• Routine or mild infections that can be treated with safer, standard antibiotics

Side Effects of ACOSTIN 1MIU INJECTION (COLISTIMETHATE SODIUM 1000000 IU)

COMMON SIDE EFFECTS

• Numbness or tingling around the mouth
• Dizziness
• Skin rash or itching
• Nausea

LESS COMMON SIDE EFFECTS

• Muscle weakness
• Blurred vision
• Slurred speech
• Fever

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Difficulty breathing or swallowing
• Signs of kidney problems such as reduced urine output or swelling
• Severe allergic reaction with swelling of face, lips, or throat
• Severe dizziness or difficulty walking
• Signs of nerve problems such as tingling, weakness, or numbness that worsens

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use ACOSTIN 1MIU INJECTION (COLISTIMETHATE SODIUM 1000000 IU)

HOW TO TAKE IT

• This medicine is given as an injection or infusion, usually in a hospital or clinic
• It may also be given as an inhaled solution in certain lung infections
• Always take it exactly as prescribed by your doctor, at the right time and dose
• Do not stop the course early even if you feel better, unless advised by your doctor
• Complete the full course to prevent bacteria from becoming resistant

IF YOU MISS A DOSE

• Since this medicine is usually given under medical supervision, missed doses are managed by your healthcare team
• If you are on home-based therapy and miss a dose, contact your doctor or nurse for guidance
• Do not double the dose to make up for a missed one

STORAGE

• Store as directed on the label, usually in a cool, dry place away from direct sunlight
• If reconstituted at home, follow the specific storage instructions given by your pharmacist
• Keep out of reach of children
• Discard any unused reconstituted solution as instructed

Safety Information and Precautions for ACOSTIN 1MIU INJECTION (COLISTIMETHATE SODIUM 1000000 IU)

This medicine is available only with a doctor's prescription in India and should be used strictly under medical supervision.

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to colistimethate sodium or other polymyxin antibiotics
• Have myasthenia gravis, unless specifically advised by your doctor

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have kidney problems or a history of kidney disease
• Have any nerve or muscle disorders
• Are pregnant, planning pregnancy, or breastfeeding
• Are taking other medicines, including over-the-counter drugs or supplements

MEDICINES THAT CAN INTERACT

• Other antibiotics that can affect the kidneys
• Muscle relaxants used during surgery
• Medicines that affect nerve or muscle function
• Diuretics or other drugs that affect kidney function

FREQUENTLY ASKED QUESTIONS

Can I take this medicine at home?

Usually no, this medicine is given in a hospital or clinic under medical supervision due to the need for monitoring.

Will this medicine affect my kidneys?

It can affect kidney function in some people, so your doctor will monitor your kidney health during treatment.

Can I stop the medicine once I feel better?

• No, you should complete the full course as prescribed to avoid the infection returning or becoming resistant.
• Doctor ya pharmacist se salah lein.