BONISTA CARTRIDGE

Uses and Benefits of BONISTA CARTRIDGE (TERIPARATIDE 250MCG\ML.)

Teriparatide is used mainly for the treatment of osteoporosis, a condition in which bones become weak and brittle and are more likely to fracture.

WHAT THIS MEDICINE IS USED FOR

• Treatment of osteoporosis in postmenopausal women at high risk of fractures
• Treatment of osteoporosis in men at high risk of fractures
• Treatment of bone loss caused by long-term steroid (glucocorticoid) use in patients at high fracture risk

HOW IT WORKS

• Teriparatide is a man-made form of parathyroid hormone
• It stimulates bone-forming cells (osteoblasts), helping to build new bone
• Over time this increases bone density and reduces the risk of fractures, especially in the spine

WHAT IT IS NOT USED FOR

• It is not used for general bone pain not related to osteoporosis
• It is not used for children or young adults with growing bones
• It is not a treatment for other types of bone diseases such as Paget's disease
• It is not used as a first-line treatment for mild bone thinning (osteopenia)

Side Effects of BONISTA CARTRIDGE (TERIPARATIDE 250MCG\ML.)

COMMON SIDE EFFECTS

• Pain, redness or swelling at the injection site
• Nausea
• Joint pain or muscle aches
• Headache
• Dizziness, especially after the first few doses

LESS COMMON SIDE EFFECTS

• Leg cramps
• Fatigue or weakness
• Increased sweating
• Mild increase in blood calcium levels
• Low blood pressure symptoms like light-headedness on standing up

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Signs of allergic reaction such as rash, swelling of face/lips/tongue, or difficulty breathing
• Severe or persistent vomiting
• Symptoms of very high calcium levels such as confusion, excessive thirst, or irregular heartbeat
• Fainting or severe dizziness after injection
• Signs of kidney stones such as severe back or abdominal pain, blood in urine

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use BONISTA CARTRIDGE (TERIPARATIDE 250MCG\ML.)

HOW TO TAKE IT

• Use exactly as prescribed by your doctor, usually once daily by injection under the skin
• Injected into the thigh or abdomen, at around the same time each day
• Sit or lie down for the first dose in case you feel dizzy
• Use a new needle each time and follow the pen device instructions given by your pharmacist
• Do not inject into a vein or muscle
• Do not shake the pen; keep it in an upright position

IF YOU MISS A DOSE

• Take the missed dose as soon as you remember on the same day
• Do not take two doses on the same day to make up for a missed one
• If you forget for that day, skip it and continue with your normal schedule the next day
• Contact your doctor if you miss several doses in a row

STORAGE

• Store in a refrigerator, away from the freezer compartment
• Keep the pen in its outer carton to protect from light
• Do not freeze; discard if it has been frozen
• Keep out of reach of children
• Dispose of used needles safely as advised by your pharmacist

Safety Information and Precautions for BONISTA CARTRIDGE (TERIPARATIDE 250MCG\ML.)

This is a prescription-only medicine in India and should be used only under the supervision of a qualified doctor.

DO NOT TAKE THIS MEDICINE IF YOU

• Have high blood calcium levels (hypercalcemia)
• Have bone cancer or cancer that has spread to the bones
• Have Paget's disease of bone
• Have unexplained high levels of alkaline phosphatase
• Have previously received radiation therapy to the bones
• Are pregnant or breastfeeding
• Are a child or adolescent with growing bones

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have kidney stones or kidney disease
• Have a history of high blood calcium
• Have severe liver disease
• Are on any other bone treatment
• Have low blood pressure or fainting episodes

MEDICINES THAT CAN INTERACT

• Digoxin (heart medicine) — calcium changes can affect its action
• Other calcium or vitamin D supplements — may increase calcium levels
• Other osteoporosis medicines, especially bisphosphonates
• Always share your full list of medicines and supplements with your doctor

FREQUENTLY ASKED QUESTIONS

How long is teriparatide usually given for?

It is generally used for a limited period, often up to 24 months in a lifetime, as decided by your doctor.

Can I take teriparatide with calcium supplements?

Your doctor may still recommend calcium and vitamin D, but the combined intake should be monitored to avoid high calcium levels.

Will I need blood tests during treatment?

• Yes, your doctor may check calcium levels and kidney function periodically during treatment.
• Doctor ya pharmacist se salah lein.