FOSARAN INJECTION

Uses and Benefits of FOSARAN INJECTION (FOSAPREPITANT DIMEGLUMINE 150MG)

Fosaprepitant Dimeglumine is used to prevent nausea and vomiting linked to certain medical treatments.

WHAT THIS MEDICINE IS USED FOR

• Preventing nausea and vomiting caused by highly emetogenic (strong) chemotherapy
• Preventing nausea and vomiting caused by moderately emetogenic chemotherapy
• Used along with other anti-sickness medicines like steroids and 5-HT3 blockers

HOW IT WORKS

• It blocks a chemical called substance P from acting on NK1 receptors in the brain
• This action reduces the signals that trigger nausea and vomiting
• It works best when combined with other anti-nausea medicines for full protection

WHAT IT IS NOT USED FOR

• It is not used to treat vomiting from motion sickness
• It is not used for morning sickness during pregnancy
• It is not a routine painkiller or general anti-sickness medicine for everyday use
• It is not meant to treat vomiting due to infections or food poisoning

Side Effects of FOSARAN INJECTION (FOSAPREPITANT DIMEGLUMINE 150MG)

COMMON SIDE EFFECTS

• Tiredness or weakness
• Headache
• Loss of appetite
• Constipation or diarrhoea
• Hiccups

LESS COMMON SIDE EFFECTS

• Dizziness
• Redness, pain, or swelling at the injection site
• Increased liver enzyme levels seen in blood tests
• Low blood pressure

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Signs of allergic reaction such as rash, itching, swelling of face or throat
• Severe difficulty breathing
• Chest tightness or irregular heartbeat
• Severe skin reactions with blistering or peeling

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use FOSARAN INJECTION (FOSAPREPITANT DIMEGLUMINE 150MG)

HOW TO TAKE IT

• This medicine is given only as an injection or drip (infusion) into a vein by a trained healthcare professional
• It is usually given before chemotherapy starts, as part of a combination anti-nausea regimen
• Do not attempt to self-administer this medicine at home
• Follow the exact schedule and combination of medicines advised by your oncologist

IF YOU MISS A DOSE

• Since this is given in a hospital or clinic setting, timing is managed by your healthcare team
• If you are unable to attend your scheduled chemotherapy or infusion appointment, contact your doctor or hospital immediately to reschedule
• Do not try to make up a missed dose on your own

STORAGE

• This medicine is stored and handled by hospital pharmacy staff under controlled conditions
• It is typically stored away from light and at a temperature specified by the manufacturer
• Patients do not usually need to store this medicine at home

Safety Information and Precautions for FOSARAN INJECTION (FOSAPREPITANT DIMEGLUMINE 150MG)

This is a prescription-only medicine in India and can be administered only under medical supervision in a hospital or clinic.

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to fosaprepitant, aprepitant, or any of its ingredients
• Are taking pimozide, cisapride, or certain other medicines that interact seriously with this drug

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have liver disease or a history of liver problems
• Are pregnant, planning pregnancy, or breastfeeding
• Are taking blood thinners like warfarin
• Are on hormonal contraceptives, as effectiveness may be reduced
• Have any heart condition

MEDICINES THAT CAN INTERACT

• Warfarin and other blood thinners
• Hormonal birth control pills or patches
• Certain chemotherapy drugs metabolised by the liver
• Steroids such as dexamethasone, which may need dose adjustment
• Pimozide and cisapride

FREQUENTLY ASKED QUESTIONS

Can I take this medicine at home?

No, it is given only in a hospital or clinic setting by trained staff as an injection or infusion.

Will this stop all vomiting from chemotherapy?

It greatly reduces the risk but is used along with other anti-nausea medicines for best results.

Does it affect birth control pills?

• Yes, it can reduce the effectiveness of hormonal contraceptives, so alternate protection may be needed.
• Doctor ya pharmacist se salah lein.