GRAFTIN 50MG TABLET

Uses and Benefits of GRAFTIN 50MG TABLET (CYCLOSPORINE 50MG.)

Cyclosporine is mainly used to prevent the body from rejecting a transplanted organ and to control certain autoimmune conditions where the immune system attacks the body's own tissues.

WHAT THIS MEDICINE IS USED FOR

• Preventing rejection after kidney, liver, heart or other organ transplants
• Severe active rheumatoid arthritis not controlled by other treatments
• Severe psoriasis where other treatments have not worked
• Nephrotic syndrome (a kidney disorder causing protein loss in urine)
• Certain severe cases of atopic dermatitis (eczema) under specialist care

HOW IT WORKS

• Suppresses specific immune cells (T-lymphocytes) that cause organ rejection or autoimmune tissue damage
• Reduces the immune system's ability to attack transplanted organs or the body's own tissues
• Does not cure the underlying disease but controls its activity

WHAT IT IS NOT USED FOR

• Not used for common infections or fevers
• Not a painkiller and not used for general joint pain
• Not used for mild skin conditions or minor allergies
• Not recommended for self-use without close medical supervision

Side Effects of GRAFTIN 50MG TABLET (CYCLOSPORINE 50MG.)

COMMON SIDE EFFECTS

• Increased blood pressure
• Headache
• Tremors or shakiness in hands
• Excessive hair growth
• Gum swelling or tenderness
• Nausea or stomach upset

LESS COMMON SIDE EFFECTS

• Fatigue or muscle cramps
• Tingling sensation in hands or feet
• Acne
• Changes in appetite
• Mild swelling of feet or ankles

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Signs of infection such as fever, chills, or persistent sore throat
• Reduced urine output or swelling suggesting kidney problems
• Yellowing of skin or eyes (jaundice)
• Severe or persistent headache with vision changes (may indicate high blood pressure or neurological effects)
• Unusual bruising or bleeding
• Seizures or confusion

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use GRAFTIN 50MG TABLET (CYCLOSPORINE 50MG.)

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, at the same time(s) each day
• Take consistently either with food or without food, as advised, and stick to the same pattern every day
• Do not take with grapefruit or grapefruit juice as it can affect absorption
• Do not stop or change the dose without consulting your doctor, even if you feel well
• Regular blood tests may be needed to check drug levels, kidney function, and blood pressure

IF YOU MISS A DOSE

• Take it as soon as you remember, unless it is almost time for your next dose
• Do not take a double dose to make up for a missed one
• If you miss doses frequently, inform your doctor as this can affect treatment success

STORAGE

• Store at room temperature, away from direct sunlight and moisture
• Keep out of reach of children
• Do not use after the expiry date printed on the pack
• Keep in the original container/blister until ready to use

Safety Information and Precautions for GRAFTIN 50MG TABLET (CYCLOSPORINE 50MG.)

This is a prescription-only medicine in India and should be used only under close medical supervision with regular monitoring.

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to cyclosporine or any ingredient in the formulation
• Have uncontrolled high blood pressure or active severe infections, unless your doctor advises otherwise
• Have significantly reduced kidney function, unless specifically prescribed by a transplant/kidney specialist

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have kidney or liver disease
• Have high blood pressure
• Have any active or recent infection
• Are pregnant, planning pregnancy, or breastfeeding
• Are taking other medicines, herbal products, or supplements

MEDICINES THAT CAN INTERACT

• Certain antibiotics and antifungal medicines
• NSAIDs (pain relievers) which may increase kidney risk
• Other immunosuppressants
• Certain blood pressure medicines and diuretics
• St. John's Wort and some herbal supplements
• Statins used for cholesterol

FREQUENTLY ASKED QUESTIONS

Can I drink alcohol while taking this medicine?

It is best to avoid or limit alcohol as it may increase strain on the liver; check with your doctor.

Will I need regular blood tests?

Yes, regular monitoring of kidney function, blood pressure, and drug levels is usually required.

Can I take this medicine long term?

• Many patients take it long term under medical supervision, especially after organ transplant; your doctor will decide the duration.
• Doctor ya pharmacist se salah lein.