GRAFYREC 300IU

Uses and Benefits of GRAFYREC 300IU (RECOMBINANT FOLLICLE STIMULATING HORMONE 300IU)

Recombinant FSH is used to treat infertility caused by problems with ovulation or low sperm count.

WHAT THIS MEDICINE IS USED FOR

• To stimulate egg development in women undergoing ovulation induction
• To support controlled ovarian stimulation before IVF or other assisted reproduction procedures
• To help increase sperm production in men with certain hormone-related infertility

HOW IT WORKS

• It mimics the natural follicle stimulating hormone produced by the body
• It stimulates the ovaries to grow and mature follicles containing eggs
• In men, it supports the testes to produce sperm along with other hormone therapy

WHAT IT IS NOT USED FOR

• It is not a general fertility tonic and is not used without medical supervision
• It is not used to treat hormonal imbalance unrelated to fertility
• It is not a contraceptive and does not prevent pregnancy
• It is not used in men or women with certain tumours or uncontrolled hormonal conditions

This medicine is used only under specialist supervision as part of a structured fertility treatment plan, with regular monitoring through blood tests and ultrasound scans.

Side Effects of GRAFYREC 300IU (RECOMBINANT FOLLICLE STIMULATING HORMONE 300IU)

COMMON SIDE EFFECTS

• Pain, redness or swelling at the injection site
• Headache
• Mild abdominal pain or bloating
• Breast tenderness

LESS COMMON SIDE EFFECTS

• Nausea or vomiting
• Mood swings or irritability
• Weight gain
• Mild fluid retention

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Severe abdominal pain, bloating or difficulty breathing (signs of ovarian hyperstimulation syndrome)
• Sudden weight gain with reduced urination
• Chest pain, leg swelling or pain (possible blood clot)
• Severe allergic reaction such as rash, swelling of face/throat, or difficulty breathing
• Multiple pregnancy symptoms should also be discussed early with your doctor

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use GRAFYREC 300IU (RECOMBINANT FOLLICLE STIMULATING HORMONE 300IU)

HOW TO TAKE IT

• This medicine is given as an injection under the skin or into a muscle, as instructed by your doctor
• It is usually self-administered after proper training, or given by a nurse
• Use the exact dose, timing and duration prescribed by your fertility specialist
• Do not adjust the dose yourself, even if you feel the treatment is working slowly or quickly
• Regular blood tests and ultrasound scans are needed to monitor your response

IF YOU MISS A DOSE

• Contact your doctor or fertility clinic immediately if you miss a dose
• Do not double the dose or delay without medical advice, as timing is critical in fertility treatment

STORAGE

• Store in a refrigerator between 2-8°C unless your product label says otherwise
• Do not freeze
• Keep the injection pen or vial away from direct light and heat
• Keep out of reach of children
• Discard any used needles safely as advised by your pharmacist

Safety Information and Precautions for GRAFYREC 300IU (RECOMBINANT FOLLICLE STIMULATING HORMONE 300IU)

This medicine is available only with a valid doctor's prescription in India and must be used under specialist supervision.

DO NOT TAKE THIS MEDICINE IF YOU

• Have a known allergy to FSH or any ingredient in the injection
• Have a tumour of the ovary, testis, breast, uterus, pituitary gland or hypothalamus
• Have unexplained vaginal bleeding
• Have primary ovarian failure or enlarged ovaries/ovarian cysts not caused by polycystic ovarian syndrome

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have thyroid, adrenal or pituitary gland problems
• Have a history of blood clots or clotting disorders
• Have polycystic ovary syndrome
• Are overweight or have any chronic illness
• Are already pregnant or think you might be pregnant

MEDICINES THAT CAN INTERACT

• Other fertility medicines such as hCG or GnRH agonists/antagonists used in the same cycle
• Any hormonal medicines you are taking for other conditions
• Always inform your doctor about all medicines, supplements, or herbal products you use

FREQUENTLY ASKED QUESTIONS

Can this medicine guarantee pregnancy?

No, it improves the chance of ovulation or sperm production but does not guarantee pregnancy.

Does this increase the chance of twins?

Yes, it can increase the chance of multiple pregnancy, so monitoring is important.

Can I take this without a fertility specialist's supervision?

• No, this medicine must only be used under close medical monitoring due to risk of overstimulation and other complications.
• Doctor ya pharmacist se salah lein.