PALONEW 0.25MG INJECTION

Uses and Benefits of PALONEW 0.25MG INJECTION (PALONOSETRON 0.5MG.)

Palonosetron is used to prevent and control nausea and vomiting associated with cancer chemotherapy and surgery.

WHAT THIS MEDICINE IS USED FOR

• Preventing nausea and vomiting caused by chemotherapy (both immediate and delayed type)
• Preventing nausea and vomiting after surgery (postoperative nausea and vomiting)

HOW IT WORKS

• Blocks serotonin (5-HT3) receptors in the gut and brain that trigger the vomiting reflex
• Has a long duration of action, helping control nausea for several days after chemotherapy
• Works by preventing signals that cause the urge to vomit rather than treating vomiting once it starts

WHAT IT IS NOT USED FOR

• Not used for motion sickness
• Not used for nausea caused by pregnancy
• Not a treatment for general stomach upset, infection, or food poisoning
• Not used as a routine painkiller or for any unrelated illness

Side Effects of PALONEW 0.25MG INJECTION (PALONOSETRON 0.5MG.)

COMMON SIDE EFFECTS

• Headache
• Constipation
• Dizziness
• Fatigue or weakness

LESS COMMON SIDE EFFECTS

• Diarrhea
• Abdominal pain
• Sleeplessness or drowsiness
• Joint pain

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Signs of allergic reaction such as rash, itching, swelling of face/lips/throat, or difficulty breathing
• Irregular heartbeat, chest pain, or fainting
• Severe headache with vision changes
• Signs of serotonin syndrome such as confusion, agitation, muscle stiffness, rapid heartbeat, or high fever

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use PALONEW 0.25MG INJECTION (PALONOSETRON 0.5MG.)

HOW TO TAKE IT

• This medicine is usually given as a single injection into a vein by a doctor or nurse, generally before chemotherapy or surgery begins
• It is not typically taken as a home medicine, so follow the exact schedule given by your treating doctor
• Do not attempt to self-inject this medicine

IF YOU MISS A DOSE

• Since this medicine is administered by a healthcare professional as part of your treatment plan, missed doses are managed by your medical team
• Contact your hospital or doctor if you are unsure about your dosing schedule

STORAGE

• Storage is generally handled by the hospital or pharmacy, as this is an injectable medicine
• If dispensed for home storage, keep away from direct light and heat, and keep out of reach of children
• Do not use if the solution appears discolored or contains particles
• Always check the expiry date before use

Safety Information and Precautions for PALONEW 0.25MG INJECTION (PALONOSETRON 0.5MG.)

Palonosetron 0.5mg is a prescription-only medicine in India and should only be used under medical supervision, usually in a hospital or clinic setting.

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to palonosetron or any other 5-HT3 receptor blocking medicines
• Have been advised against it by your doctor due to a specific medical condition

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have any heart rhythm problems or a history of heart disease
• Have liver or kidney disease
• Are pregnant, planning pregnancy, or breastfeeding
• Are taking other medicines that affect heart rhythm or serotonin levels

MEDICINES THAT CAN INTERACT

• Other serotonergic medicines such as certain antidepressants (SSRIs, SNRIs) — risk of serotonin syndrome
• Medicines that affect heart rhythm (QT prolonging drugs)
• Other anti-nausea medicines from the same class

FREQUENTLY ASKED QUESTIONS

Can I take this medicine at home?

No, it is usually given as an injection by a healthcare professional in a hospital or clinic setting.

How long does its effect last?

It has a long duration of action and can help prevent nausea for several days after chemotherapy.

Is it safe for pregnant women?

• It should only be used in pregnancy if clearly needed and advised by a doctor.
• Doctor ya pharmacist se salah lein.