Amphotericin Bpage 95 Of 123

Amphotericin Bpage 95 Of 123 — Uses and Benefits

Amphotericin B is used to treat serious fungal infections that affect the blood, lungs, brain or other internal organs, especially in patients with weak immunity.

WHAT THIS MEDICINE IS USED FOR

• Treating severe systemic fungal infections such as candidiasis, aspergillosis, cryptococcal meningitis and histoplasmosis
• Treating fungal infections in patients with cancer, HIV, organ transplant or those on immunosuppressive therapy
• Treating certain parasitic infections like visceral leishmaniasis (kala-azar) in some cases
• Used when other antifungal medicines have failed or are not suitable

HOW IT WORKS

• It binds to a component of the fungal cell membrane called ergosterol
• This creates pores in the fungal cell membrane, causing leakage of cell contents
• This action kills the fungus or stops it from growing further

WHAT IT IS NOT USED FOR

• Not used for common skin fungal infections like ringworm
• Not used for ordinary vaginal yeast infections
• Not effective against bacterial or viral infections
• Not a first-choice medicine for mild fungal infections

How to Use Amphotericin Bpage 95 Of 123

HOW TO TAKE IT

• This medicine is given only as an intravenous infusion by a trained healthcare professional in a hospital or clinic
• It is not available as a tablet or syrup for self-use
• The infusion is usually given slowly over several hours, with monitoring of blood pressure, temperature and kidney function
• Your doctor may give a test dose first to check for allergic reaction
• Blood tests may be done regularly during treatment to monitor kidney function and electrolyte levels
• Complete the full course as advised by your doctor, even if you feel better

IF YOU MISS A DOSE

• Since this medicine is given under medical supervision, missed doses are managed by the hospital or clinic staff
• Do not try to self-administer or make up a missed dose
• Inform your healthcare team if you are unable to attend a scheduled infusion

STORAGE

• This medicine is stored and handled by hospital pharmacy staff under controlled conditions
• It should be protected from light and stored at the temperature specified on the label
• Patients and caregivers do not need to store this medicine at home

Amphotericin Bpage 95 Of 123 — Side Effects

COMMON SIDE EFFECTS

• Fever and chills during infusion
• Headache
• Nausea and vomiting
• Muscle or joint pain
• Low blood pressure during infusion

LESS COMMON SIDE EFFECTS

• Loss of appetite
• Diarrhoea or stomach upset
• Low potassium or magnesium levels in blood
• Pain or redness at the injection site
• Anaemia with prolonged use

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Signs of kidney damage such as reduced urination or swelling
• Severe allergic reaction with breathlessness, swelling of face/throat, or rash
• Irregular heartbeat or chest pain
• Severe drop in blood pressure or fainting
• Seizures or unusual confusion

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

Amphotericin Bpage 95 Of 123 — Safety Information and Precautions

This is a prescription-only medicine in India and must be given only under close medical supervision, usually in a hospital setting.

DO NOT TAKE THIS MEDICINE IF YOU

• Have had a severe allergic reaction to amphotericin B or similar medicines in the past
• Are not under medical supervision, since this medicine requires monitoring during administration

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have kidney disease or reduced kidney function
• Have any heart condition
• Have low potassium or magnesium levels
• Are pregnant, planning pregnancy, or breastfeeding
• Are taking other medicines that may affect the kidneys

MEDICINES THAT CAN INTERACT

• Other medicines that can harm the kidneys, such as certain antibiotics
• Corticosteroids, which may worsen potassium loss
• Medicines that affect heart rhythm
• Other antifungal medicines
• Drugs that suppress the immune system

FREQUENTLY ASKED QUESTIONS

Can I take this medicine at home?

No, it is given only in a hospital or clinic under medical supervision as an IV infusion.

Why do I need frequent blood tests during treatment?

Blood tests help the doctor monitor your kidney function and electrolyte levels, which can be affected by this medicine.

How long does treatment usually last?

• The duration depends on the type and severity of infection and is decided by your treating doctor.
• Doctor ya pharmacist se salah lein.