Colistimethate Sodium 1Million iu

Colistimethate Sodium 1Million iu — Uses and Benefits

Colistimethate Sodium is used to treat serious bacterial infections that have not responded to other antibiotics, especially those caused by multi-drug resistant organisms like Pseudomonas aeruginosa and Acinetobacter species.

WHAT THIS MEDICINE IS USED FOR

• Severe hospital-acquired infections such as pneumonia, bloodstream infections, and urinary tract infections
• Infections in intensive care unit patients caused by resistant bacteria
• Lung infections in patients with cystic fibrosis (given by inhalation)
• Used when other antibiotics have failed due to resistance

HOW IT WORKS

• Colistimethate Sodium works by damaging the outer membrane of certain bacteria
• This causes leakage of essential contents from the bacterial cell, leading to bacterial death
• It is effective mainly against gram-negative bacteria

WHAT IT IS NOT USED FOR

• Not used for viral infections such as flu or common cold
• Not used for mild infections that can be treated with safer, first-line antibiotics
• Not a first-choice treatment due to potential for kidney and nerve side effects
• Not recommended for infections caused by bacteria not sensitive to it

How to Use Colistimethate Sodium 1Million iu

HOW TO TAKE IT

• This medicine is given only under medical supervision, usually in a hospital
• It may be given as an injection into a vein or muscle, or as an inhaled solution using a nebuliser
• Follow the exact dose, frequency, and duration prescribed by your doctor
• Do not stop the course early even if you feel better, unless your doctor advises
• Complete the full course to help prevent bacterial resistance

IF YOU MISS A DOSE

• Since this medicine is usually administered by a healthcare professional, missed doses are unlikely
• If you are on a home nebuliser treatment and miss a dose, inform your doctor or take it as soon as you remember, unless it is close to the next dose
• Do not double the dose to make up for a missed one

STORAGE

• Store as directed by your pharmacist or hospital pharmacy, usually in a cool, dry place away from direct sunlight
• Reconstituted solutions should be used within the time specified by the manufacturer and not stored for later use
• Keep out of reach of children
• Do not use if the solution appears discoloured or has particles in it

Colistimethate Sodium 1Million iu — Side Effects

COMMON SIDE EFFECTS

• Numbness or tingling around the mouth
• Dizziness
• Skin rash or itching
• Pain at the injection site

LESS COMMON SIDE EFFECTS

• Blurred vision
• Slurred speech
• Muscle weakness
• Fever

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Difficulty breathing or wheezing (possible allergic reaction)
• Reduced urine output or swelling of legs/face (possible kidney injury)
• Severe muscle weakness or difficulty moving limbs (possible nerve or neuromuscular effect)
• Signs of severe allergic reaction such as swelling of face, lips, tongue, or throat

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

Colistimethate Sodium 1Million iu — Safety Information and Precautions

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to colistimethate sodium or other polymyxin antibiotics
• Have a history of severe allergic reactions to similar antibiotics

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have kidney disease or reduced kidney function
• Have a nerve or muscle disorder such as myasthenia gravis
• Are pregnant, planning pregnancy, or breastfeeding
• Are taking other medicines that can affect the kidneys or nerves

MEDICINES THAT CAN INTERACT

• Other antibiotics that can affect the kidneys, such as aminoglycosides
• Muscle relaxants used during surgery, as effects may be increased
• Other drugs that can cause nerve-related side effects
• Always inform your doctor about all medicines, supplements, or herbal products you are taking

This medicine is available only with a valid doctor's prescription in India and should be administered under medical supervision.

FREQUENTLY ASKED QUESTIONS

Can I take this medicine at home without supervision?

No, this medicine is usually given in a hospital or clinical setting due to the need for monitoring of kidney function and possible side effects.

Will this medicine cure all types of infections?

No, it is effective only against specific bacteria and is reserved for serious, resistant infections as determined by your doctor.

Can this medicine affect my kidneys?

• Yes, it can affect kidney function, so your doctor will monitor your kidney health with blood tests during treatment.
• Doctor ya pharmacist se salah lein.