Levodopa 150mg + Carbidopa 37.5mg. + Entacapone 200mg

Levodopa 150mg + Carbidopa 37.5mg. + Entacapone 200mg — Uses and Benefits

This medicine is used to treat Parkinson's disease, a condition where certain brain cells that produce dopamine are lost, causing problems with movement and coordination.

WHAT THIS MEDICINE IS USED FOR

• Managing symptoms of Parkinson's disease such as tremors, stiffness and slow movement
• Improving mobility and daily functioning in people with Parkinson's disease
• Used when a patient is already on levodopa-carbidopa therapy and needs better symptom control

HOW IT WORKS

• Levodopa is converted into dopamine in the brain, replacing what is lost in Parkinson's disease
• Carbidopa prevents levodopa from being broken down before it reaches the brain, so more of it works effectively
• Entacapone blocks another enzyme that breaks down levodopa, extending its effect and reducing symptom fluctuations

WHAT IT IS NOT USED FOR

• Not used for other types of tremors not related to Parkinson's disease
• Not a cure for Parkinson's disease, it only manages symptoms
• Not recommended for drug-induced movement disorders unrelated to Parkinson's
• Not to be used without a proper diagnosis by a neurologist

How to Use Levodopa 150mg + Carbidopa 37.5mg. + Entacapone 200mg

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually multiple times a day
• Swallow the tablet with water; it can be taken with or without food, but consistency helps
• Avoid taking with high-protein meals as they may reduce absorption
• Do not crush or split the tablet unless your doctor advises
• Do not stop suddenly without consulting your doctor as it may worsen symptoms

IF YOU MISS A DOSE

• Take it as soon as you remember
• If it is almost time for your next dose, skip the missed one and continue your normal schedule
• Do not double the dose to make up for a missed one
• If you miss doses often, discuss a reminder system with your doctor

STORAGE

• Store at room temperature, away from direct sunlight and moisture
• Keep in the original packaging until use
• Keep out of reach of children and pets
• Do not use after the expiry date printed on the pack

Levodopa 150mg + Carbidopa 37.5mg. + Entacapone 200mg — Side Effects

COMMON SIDE EFFECTS

• Nausea
• Dizziness
• Diarrhoea
• Dark urine (harmless colour change)
• Dry mouth

LESS COMMON SIDE EFFECTS

• Vivid dreams or sleep disturbances
• Involuntary movements (dyskinesia)
• Low blood pressure on standing up
• Headache
• Loss of appetite

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Severe confusion, hallucinations or unusual behaviour
• Chest pain or irregular heartbeat
• Signs of an allergic reaction like swelling, rash or difficulty breathing
• High fever with stiff muscles and confusion (possible neuroleptic-like reaction)
• Sudden uncontrollable urges (gambling, shopping, hypersexuality)

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

Levodopa 150mg + Carbidopa 37.5mg. + Entacapone 200mg — Safety Information and Precautions

This medicine is available only with a doctor's prescription in India.

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to levodopa, carbidopa, entacapone or any other ingredient
• Have narrow-angle glaucoma
• Have a history of certain adrenal gland tumours (pheochromocytoma)
• Are taking certain older antidepressants called non-selective MAO inhibitors

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have heart disease, irregular heartbeat or low blood pressure
• Have liver or kidney problems
• Have a history of mental illness, hallucinations or severe depression
• Have asthma or breathing problems
• Are pregnant, planning pregnancy or breastfeeding
• Have a history of peptic ulcer or stomach bleeding

MEDICINES THAT CAN INTERACT

• Certain antidepressants and antipsychotics
• Blood pressure medicines
• Iron supplements (can reduce absorption)
• Other Parkinson's medicines
• Medicines that affect liver enzymes

FREQUENTLY ASKED QUESTIONS

Can I stop this medicine on my own if I feel better?

No, stopping suddenly can worsen Parkinson's symptoms; always consult your doctor before making changes.

Will my urine colour change with this medicine?

Yes, harmless darkening of urine or sweat is common and not a cause for worry.

Can this medicine be taken with other Parkinson's treatments?

• Sometimes, but only under your doctor's guidance as combinations need careful dose adjustment.
• Doctor ya pharmacist se salah lein.