Pyrazinamide 1000mg

Pyrazinamide 1000mg — Uses and Benefits

Pyrazinamide is used to treat active tuberculosis (TB) infection, always in combination with other anti-TB drugs.

WHAT THIS MEDICINE IS USED FOR

• Treatment of active pulmonary and extrapulmonary tuberculosis
• Used during the initial intensive phase of TB treatment
• Given as part of a multi-drug regimen, never alone

HOW IT WORKS

• Kills or stops the growth of Mycobacterium tuberculosis bacteria, especially those hiding inside cells and in acidic environments like abscesses
• Helps shorten the overall duration of TB treatment when combined with other drugs
• Works best when taken regularly at the same time each day

WHAT IT IS NOT USED FOR

• Not used for latent (inactive) TB infection
• Not effective against viral infections like cold or flu
• Not a painkiller or fever medicine
• Not to be used as a standalone treatment for any infection

Always complete the full course as advised by your doctor, even if you feel better, to prevent drug-resistant TB.

How to Use Pyrazinamide 1000mg

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually once daily
• Can be taken with or without food, but taking with food may reduce stomach upset
• Swallow the tablet with water; do not crush unless advised
• Take at the same time each day to maintain a regular treatment schedule
• Do not stop the medicine on your own even if symptoms improve — complete the full course
• Take along with other prescribed anti-TB medicines as directed

IF YOU MISS A DOSE

• Take it as soon as you remember on the same day
• If it is almost time for your next dose, skip the missed dose and continue as usual
• Do not double the dose to make up for a missed one
• Try to maintain regular dosing as missed doses can affect treatment success

STORAGE

• Store at room temperature, away from direct sunlight and moisture
• Keep out of reach of children
• Do not use after the expiry date printed on the pack

Pyrazinamide 1000mg — Side Effects

COMMON SIDE EFFECTS

• Loss of appetite
• Nausea
• Joint pain
• Mild fatigue

LESS COMMON SIDE EFFECTS

• Skin rash or itching
• Increased uric acid levels
• Fever
• Flushing of skin

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Yellowing of skin or eyes, dark urine (signs of liver damage)
• Severe abdominal pain or vomiting
• Severe joint swelling or gout-like attacks
• Signs of severe allergic reaction such as swelling of face/lips, difficulty breathing, severe rash
• Unusual bleeding or bruising

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

Pyrazinamide 1000mg — Safety Information and Precautions

This medicine is available only with a doctor's prescription in India.

DO NOT TAKE THIS MEDICINE IF YOU

• Have severe liver disease
• Have acute gout
• Are allergic to pyrazinamide or any of its ingredients

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have any existing liver problems
• Have diabetes
• Have a history of gout or high uric acid levels
• Are pregnant or breastfeeding
• Have kidney disease
• Consume alcohol regularly

MEDICINES THAT CAN INTERACT

• Other anti-TB drugs (used together but monitored closely for liver effects)
• Medicines for gout, as pyrazinamide can raise uric acid levels
• Certain diabetes medicines, as blood sugar control may be affected
• Other medicines that affect the liver

Always inform your doctor about all medicines, supplements, and herbal products you are taking.

FREQUENTLY ASKED QUESTIONS

Can I stop this medicine once I feel better?

No, stopping early can lead to drug-resistant TB; always complete the full course as advised by your doctor.

Will this medicine affect my liver?

It can affect liver function, so your doctor may order regular blood tests to monitor liver health during treatment.

Can I drink alcohol while taking this medicine?

• It is best to avoid alcohol as it increases the risk of liver damage during TB treatment.
• Doctor ya pharmacist se salah lein.