Rifampicin 150mg + Isoniazid 75mg + Ethambutol 275mg

Rifampicin 150mg + Isoniazid 75mg + Ethambutol 275mg — Uses and Benefits

This medicine is used to treat active pulmonary and certain forms of extra-pulmonary tuberculosis (TB), usually as part of a multi-drug regimen.

WHAT THIS MEDICINE IS USED FOR

• Treatment of active tuberculosis infection
• Used in combination with other anti-TB drugs as part of a complete treatment course
• Helps prevent the TB bacteria from developing resistance to a single drug

HOW IT WORKS

• Rifampicin and Isoniazid kill the TB bacteria by stopping their growth and multiplication
• Ethambutol stops the bacteria from building their protective cell wall
• Together, the three drugs attack the bacteria in different ways, making treatment more effective and reducing chances of drug resistance

WHAT IT IS NOT USED FOR

• Not used for viral infections like cold or flu
• Not a preventive medicine for people without active TB unless specifically advised by a doctor
• Not to be used for other bacterial infections not related to TB
• Not a substitute for completing the full prescribed course of treatment

How to Use Rifampicin 150mg + Isoniazid 75mg + Ethambutol 275mg

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually once daily
• Preferably take on an empty stomach, at least 30 minutes before food, unless your doctor advises otherwise
• Swallow the tablet whole with a full glass of water
• Do not stop the medicine even if you feel better - complete the full course as advised
• Take at the same time each day to maintain steady levels in the body

IF YOU MISS A DOSE

• Take it as soon as you remember on the same day
• If it is almost time for your next dose, skip the missed dose and continue as usual
• Do not take a double dose to make up for a missed one
• Missing doses regularly can reduce effectiveness and increase risk of drug resistance, so try to be consistent

STORAGE

• Store at room temperature, away from direct sunlight and moisture
• Keep in the original packaging until ready to use
• Keep out of reach and sight of children
• Do not use after the expiry date printed on the pack

Rifampicin 150mg + Isoniazid 75mg + Ethambutol 275mg — Side Effects

COMMON SIDE EFFECTS

• Loss of appetite
• Nausea or mild stomach upset
• Orange-red discoloration of urine, sweat or tears (harmless)
• Mild joint pain

LESS COMMON SIDE EFFECTS

• Skin rash or itching
• Headache
• Dizziness
• Numbness or tingling in hands or feet

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Yellowing of skin or eyes, dark urine (signs of liver problems)
• Vision changes, blurred vision or difficulty distinguishing colours (may indicate eye toxicity)
• Severe skin reaction with blistering or peeling
• Unexplained fever, bruising or bleeding
• Severe vomiting or abdominal pain
• Signs of allergic reaction such as swelling of face, lips or throat, difficulty breathing

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

Rifampicin 150mg + Isoniazid 75mg + Ethambutol 275mg — Safety Information and Precautions

This medicine is available only with a valid doctor's prescription in India and should be taken under medical supervision throughout the treatment course.

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to Rifampicin, Isoniazid, Ethambutol or any other ingredient in this medicine
• Have severe active liver disease, unless specifically advised by your doctor
• Have optic neuritis or other eye conditions affecting vision, without doctor's clearance

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have any liver or kidney disease
• Have a history of eye problems or vision issues
• Are pregnant, planning pregnancy, or breastfeeding
• Consume alcohol regularly
• Have diabetes, gout, or a history of seizures
• Are taking any other medicines, including over-the-counter drugs and supplements

MEDICINES THAT CAN INTERACT

• Oral contraceptives (this medicine can reduce their effectiveness)
• Blood thinners like warfarin
• Diabetes medicines
• Other liver-affecting medicines or alcohol
• HIV medicines and certain antibiotics
• Antacids (may reduce absorption; take at a different time)

FREQUENTLY ASKED QUESTIONS

Can I stop the medicine once I feel better?

No, stopping early can lead to treatment failure and drug-resistant TB; always complete the full course as prescribed.

Will this medicine change the colour of my urine?

Yes, orange-red discoloration of urine, sweat and tears is common and harmless.

Can I drink alcohol while taking this medicine?

• It is best to avoid alcohol as it increases the risk of liver damage during treatment.
• Doctor ya pharmacist se salah lein.