APRELIEF KIT

Uses and Benefits of APRELIEF KIT (APREPITANT 125MG + APREPITANT 125MG)

Aprepitant is mainly used to prevent nausea and vomiting caused by strong chemotherapy medicines and sometimes after surgery.

WHAT THIS MEDICINE IS USED FOR

• Preventing nausea and vomiting linked to cancer chemotherapy
• Preventing nausea and vomiting after certain surgeries
• Used along with other anti-sickness medicines as part of a combination regimen

HOW IT WORKS

• It blocks a chemical messenger called substance P from acting on NK1 receptors in the brain
• This reduces the signal that triggers nausea and vomiting
• It is usually combined with a steroid and another anti-sickness medicine for best effect

WHAT IT IS NOT USED FOR

• It is not a painkiller and does not treat cancer itself
• It is not used for regular motion sickness or food poisoning related vomiting
• It is not meant for daily long-term use unless specifically advised by your doctor

This medicine should only be used under the supervision of a doctor, usually as part of a planned chemotherapy or surgery schedule.

Side Effects of APRELIEF KIT (APREPITANT 125MG + APREPITANT 125MG)

COMMON SIDE EFFECTS

• Tiredness or weakness
• Headache
• Constipation or diarrhoea
• Loss of appetite
• Hiccups

LESS COMMON SIDE EFFECTS

• Dizziness
• Stomach discomfort or indigestion
• Dry mouth
• Mild skin rash

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Severe allergic reaction with swelling of face, lips, or throat, or difficulty breathing
• Severe skin reaction with blistering or peeling
• Signs of liver problems such as yellowing of skin or eyes, dark urine, severe tiredness
• Very fast or irregular heartbeat

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use APRELIEF KIT (APREPITANT 125MG + APREPITANT 125MG)

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually before starting a chemotherapy cycle
• Can be taken with or without food
• Swallow the capsule whole with water; do not chew or crush unless advised
• It is usually given as part of a short course along with other anti-sickness medicines

IF YOU MISS A DOSE

• Since this is usually taken around chemotherapy timing, contact your doctor or hospital team if you miss a dose
• Do not take an extra dose to make up for a missed one without medical advice
• Follow the schedule given by your treating doctor closely

STORAGE

• Store at room temperature, away from direct heat, light, and moisture
• Keep in the original packaging until ready to use
• Keep out of reach of children and pets
• Do not use after the expiry date printed on the pack

Safety Information and Precautions for APRELIEF KIT (APREPITANT 125MG + APREPITANT 125MG)

This is a prescription-only medicine in India and should be used only under a doctor's guidance, typically as part of a hospital or chemotherapy treatment plan.

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to aprepitant or any ingredient in the capsule
• Are taking certain medicines like pimozide, which can interact seriously with aprepitant

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have liver disease or liver problems
• Are pregnant, planning pregnancy, or breastfeeding
• Are taking hormonal contraceptives, as aprepitant may reduce their effectiveness
• Are on blood thinners such as warfarin
• Have any other chronic illness or are on long-term medicines

MEDICINES THAT CAN INTERACT

• Warfarin and other blood thinners
• Hormonal birth control pills or patches
• Certain steroids like dexamethasone
• Medicines processed by the liver enzyme CYP3A4, including some antifungal and HIV medicines
• Pimozide and certain other specific drugs

FREQUENTLY ASKED QUESTIONS

Can aprepitant be taken alone for vomiting?

No, it is usually given along with other anti-sickness medicines as part of a combination regimen for chemotherapy-related nausea.

Does aprepitant affect birth control pills?

Yes, it can reduce the effectiveness of hormonal contraceptives, so an alternative method may be advised during treatment.

Is this medicine safe during pregnancy?

• It should be used in pregnancy only if clearly needed and advised by a doctor, as safety data is limited.
• Doctor ya pharmacist se salah lein.