DEPRAN 20/.5MG Tablets

Uses and Benefits of DEPRAN 20/.5MG Tablets (Escitalopram 20mg + Clonazepam 0.5mg)

This medicine is used to treat depression, particularly when it is accompanied by significant anxiety or sleep disturbance.

WHAT THIS MEDICINE IS USED FOR

• Treatment of major depressive disorder
• Short-term relief of anxiety symptoms linked with depression
• Helping improve sleep disturbances caused by anxiety or depression

HOW IT WORKS

• Escitalopram increases the level of serotonin, a chemical messenger in the brain that helps regulate mood
• Clonazepam acts on brain receptors (GABA) to produce a calming effect, reducing anxiety and helping with sleep
• Together they help stabilise mood while easing anxiety, especially in the early weeks of antidepressant therapy

WHAT IT IS NOT USED FOR

• Not a first-line or standalone treatment for long-term anxiety disorders
• Not meant for occasional or as-needed use for stress relief
• Not to be used for seizure disorders unless specifically advised by a doctor
• Not for use in children or adolescents unless prescribed by a specialist

Side Effects of DEPRAN 20/.5MG Tablets (Escitalopram 20mg + Clonazepam 0.5mg)

COMMON SIDE EFFECTS

• Drowsiness or sedation
• Nausea
• Dry mouth
• Fatigue or tiredness
• Dizziness
• Reduced appetite

LESS COMMON SIDE EFFECTS

• Difficulty sleeping or vivid dreams
• Sweating
• Constipation or diarrhoea
• Blurred vision
• Weight changes
• Reduced sex drive

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Thoughts of self-harm or worsening depression
• Severe allergic reaction (swelling, rash, breathing difficulty)
• Signs of serotonin syndrome (agitation, high fever, fast heartbeat, muscle stiffness)
• Severe drowsiness, confusion, or trouble breathing
• Unusual bleeding or bruising
• Yellowing of skin or eyes

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use DEPRAN 20/.5MG Tablets (Escitalopram 20mg + Clonazepam 0.5mg)

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually once daily
• Swallow the tablet with water; it may be taken with or without food
• Try to take it at the same time each day to maintain steady levels in the body
• Do not stop suddenly without consulting your doctor, as this may cause withdrawal effects
• It may take a few weeks to feel the full benefit for depression

IF YOU MISS A DOSE

• Take it as soon as you remember on the same day
• If it is almost time for your next dose, skip the missed one and continue as usual
• Do not take a double dose to make up for a missed one

STORAGE

• Store at room temperature, away from direct sunlight and moisture
• Keep out of reach of children
• Do not use after the expiry date printed on the pack

Safety Information and Precautions for DEPRAN 20/.5MG Tablets (Escitalopram 20mg + Clonazepam 0.5mg)

This is a prescription-only medicine in India and should not be used without a doctor's prescription.

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to Escitalopram, Clonazepam, or any other ingredient in this medicine
• Have severe liver disease
• Have myasthenia gravis or severe breathing problems
• Are taking or have recently taken MAO inhibitors
• Are pregnant or breastfeeding, unless specifically advised by your doctor

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have a history of seizures, glaucoma, or kidney/liver disease
• Have a history of substance abuse or dependence
• Have bipolar disorder or history of suicidal thoughts
• Are elderly, as sedation risk is higher
• Are taking any other medicines, including over-the-counter drugs or supplements

MEDICINES THAT CAN INTERACT

• Other antidepressants or medicines affecting serotonin levels
• Sedatives, sleeping pills, or other benzodiazepines
• Alcohol, which increases drowsiness and risk of side effects
• Blood thinners like warfarin
• Certain pain medicines like tramadol

FREQUENTLY ASKED QUESTIONS

Can I drink alcohol while taking this medicine?

No, alcohol should be avoided as it increases drowsiness and can be dangerous when combined with this medicine.

Is this medicine habit-forming?

Clonazepam can cause dependence with prolonged use, so it should be taken only as directed and not stopped abruptly.

How long will I need to take this medicine?

• Your doctor will decide the duration based on your response; the anxiety-relieving component is usually used only for a short period.
• Doctor ya pharmacist se salah lein.