IMBRUVICA 140MG CAPSULE (120 CAPSULES)

Uses and Benefits of IMBRUVICA 140MG CAPSULE (120 CAPSULES) (IBRUTINIB 140MG)

Ibrutinib is used to treat certain types of blood and lymph node cancers.

WHAT THIS MEDICINE IS USED FOR

• Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL)
• Mantle cell lymphoma
• Waldenström's macroglobulinemia
• Chronic graft-versus-host disease that has not responded to other treatments

HOW IT WORKS

• It blocks an enzyme called Bruton's tyrosine kinase (BTK)
• This enzyme helps abnormal white blood cells grow and multiply
• By blocking BTK, ibrutinib slows down or stops cancer cell growth and helps reduce their number in the blood

WHAT IT IS NOT USED FOR

• It is not used for solid tumours like breast, lung, or colon cancer
• It is not a painkiller or a general immune booster
• It should not be used for infections or for other unrelated blood disorders
• It is not a cure by itself and must be used as part of a complete treatment plan decided by your oncologist

Side Effects of IMBRUVICA 140MG CAPSULE (120 CAPSULES) (IBRUTINIB 140MG)

COMMON SIDE EFFECTS

• Diarrhea
• Fatigue and weakness
• Muscle and joint pain
• Nausea
• Bruising
• Low blood counts (anemia, low platelets)

LESS COMMON SIDE EFFECTS

• Rash
• Mouth sores
• Swelling of hands or feet
• Dizziness
• High blood pressure
• Nail and skin changes

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Unusual bleeding or bruising, blood in urine or stools
• Signs of infection such as fever, chills, or persistent cough
• Irregular heartbeat, palpitations, chest pain, or shortness of breath
• Severe swelling, sudden weight gain, or difficulty breathing
• Signs of allergic reaction such as facial swelling, severe rash, or trouble breathing
• Signs of a new cancer such as unexplained lumps or skin changes

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use IMBRUVICA 140MG CAPSULE (120 CAPSULES) (IBRUTINIB 140MG)

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually once a day
• Swallow the capsule or tablet whole with a glass of water; do not open, crush, or chew it
• Take it at the same time every day to maintain steady levels in the body
• Can be taken with or without food unless your doctor advises otherwise
• Do not stop taking it suddenly without consulting your doctor, even if you feel better
• Avoid grapefruit and grapefruit juice while on this medicine, as it can affect how the drug works

IF YOU MISS A DOSE

• Take the missed dose as soon as you remember on the same day
• If it is almost time for your next dose, skip the missed one and continue your normal schedule
• Do not take a double dose to make up for a missed one
• If you miss doses often, inform your doctor

STORAGE

• Store at room temperature, away from direct heat, light, and moisture
• Keep out of reach of children and pets
• Do not use after the expiry date printed on the pack
• Dispose of unused medicine safely as advised by your pharmacist

Safety Information and Precautions for IMBRUVICA 140MG CAPSULE (120 CAPSULES) (IBRUTINIB 140MG)

This is a prescription-only medicine in India and should be used strictly under the supervision of an oncologist or hematologist.

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to ibrutinib or any ingredient in the formulation
• Are pregnant or planning pregnancy, unless specifically advised by your doctor
• Are breastfeeding

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have a history of bleeding disorders or are on blood thinners
• Have liver disease
• Have a history of irregular heartbeat or heart disease
• Have a history of infections or a weakened immune system
• Are scheduled for any surgery or dental procedure
• Are taking any other prescription, over-the-counter, or herbal medicines

MEDICINES THAT CAN INTERACT

• Antifungal medicines such as ketoconazole or itraconazole
• Certain antibiotics such as clarithromycin
• Blood thinners such as warfarin
• Other medicines affecting liver enzymes (CYP3A4)
• Grapefruit juice and grapefruit-containing products

FREQUENTLY ASKED QUESTIONS

Can I take this medicine with food?

Yes, it can usually be taken with or without food, but follow your doctor's specific instructions.

How long do I need to take this medicine?

The duration depends on your condition and response to treatment; your doctor will decide the right length of therapy.

Can I drink alcohol while on this medicine?

• It is best to avoid or limit alcohol, as it may increase strain on the liver and worsen side effects.
• Doctor ya pharmacist se salah lein.