PREGAVEX-NT TABLET

Uses and Benefits of PREGAVEX-NT TABLET (Pregabalin 75mg + Nortriptyline 10mg)

This combination medicine is mainly prescribed for managing chronic nerve pain (neuropathic pain), such as pain from diabetes, nerve injury, or shingles, especially when sleep disturbance or low mood is also present.

WHAT THIS MEDICINE IS USED FOR

• Nerve pain (neuropathic pain) due to diabetes, shingles, or nerve injury
• Chronic pain conditions where sleep is also disturbed
• Sometimes used for fibromyalgia-related pain, as advised by doctor

HOW IT WORKS

• Pregabalin reduces abnormal electrical activity in nerves, easing pain signals
• Nortriptyline alters brain chemical levels (serotonin and noradrenaline) to reduce pain perception and improve mood and sleep
• Together they provide better pain control than either alone in some cases

WHAT IT IS NOT USED FOR

• Not for ordinary headache or muscle pain
• Not a first-line treatment for anxiety or depression alone
• Not meant for acute, short-term pain like injury or surgery pain
• Not to be used without medical supervision for sleep problems alone

Side Effects of PREGAVEX-NT TABLET (Pregabalin 75mg + Nortriptyline 10mg)

COMMON SIDE EFFECTS

• Drowsiness or sedation
• Dizziness
• Dry mouth
• Weight gain
• Constipation
• Blurred vision

LESS COMMON SIDE EFFECTS

• Swelling of hands or feet
• Difficulty concentrating
• Low blood pressure on standing up
• Increased appetite
• Tremors

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Fast or irregular heartbeat
• Fainting or severe dizziness
• Signs of allergic reaction like rash, swelling of face or throat, breathing difficulty
• Suicidal thoughts or worsening mood
• Severe confusion or hallucinations
• Difficulty passing urine

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use PREGAVEX-NT TABLET (Pregabalin 75mg + Nortriptyline 10mg)

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually once daily at bedtime
• Swallow the tablet with water; do not crush or chew unless advised
• Can be taken with or without food, but taking it at the same time daily helps
• Do not stop suddenly without consulting your doctor, as this may cause withdrawal effects
• Avoid alcohol while taking this medicine as it increases drowsiness

IF YOU MISS A DOSE

• Take it as soon as you remember
• If it is almost time for the next dose, skip the missed one
• Do not take two doses together to make up for a missed one

STORAGE

• Store at room temperature, away from direct sunlight and moisture
• Keep out of reach of children and pets
• Do not use after the expiry date printed on the pack
• Dispose of unused medicine safely, do not flush down the drain

Safety Information and Precautions for PREGAVEX-NT TABLET (Pregabalin 75mg + Nortriptyline 10mg)

This is a prescription-only medicine in India and should not be taken without a valid doctor's prescription.

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to Pregabalin, Nortriptyline, or any other ingredient
• Have had a recent heart attack
• Are taking or have recently stopped MAOI antidepressants
• Have severe liver or heart rhythm problems, unless advised by a specialist

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have kidney or liver disease
• Have a history of heart disease, glaucoma, or urinary retention
• Have depression, suicidal thoughts, or any mental health condition
• Are pregnant, planning pregnancy, or breastfeeding
• Drink alcohol regularly or take sedative medicines
• Are elderly, as sensitivity to side effects may be higher

MEDICINES THAT CAN INTERACT

• Other antidepressants or MAOIs
• Sedatives, sleeping pills, or anti-anxiety medicines
• Opioid painkillers
• Medicines for high blood pressure
• Antihistamines that cause drowsiness
• Alcohol

FREQUENTLY ASKED QUESTIONS

Can this medicine be taken long term?

Yes, it is often used for chronic pain over months, but only under regular doctor supervision.

Will this medicine make me sleepy during the day?

It can, especially when starting; avoid driving or operating machinery until you know how it affects you.

Can I stop taking it once pain improves?

• Do not stop suddenly; your doctor will guide you on tapering the dose safely.
• Doctor ya pharmacist se salah lein.