SYNCAPONE 100MG TABLET

Uses and Benefits of SYNCAPONE 100MG TABLET (LEVODOPA 100MG+CARBIDOPA 25MG+ENTACAPONE 200MG)

This combination medicine is used to treat Parkinson's disease, a condition that affects movement due to low dopamine levels in the brain.

WHAT THIS MEDICINE IS USED FOR

• Managing symptoms of Parkinson's disease such as stiffness, tremors and slow movement
• Improving the ability to perform daily activities in people with Parkinson's disease
• Used in patients who experience 'end-of-dose wearing off' with levodopa-carbidopa alone

HOW IT WORKS

• Levodopa converts into dopamine in the brain, replacing what is lost in Parkinson's disease
• Carbidopa prevents levodopa from breaking down too early outside the brain, so more reaches the brain
• Entacapone blocks an enzyme that breaks down levodopa, making its effect last longer

WHAT IT IS NOT USED FOR

• Not used for other types of tremors unrelated to Parkinson's disease
• Not used for drug-induced movement disorders unless specifically advised
• Not a cure for Parkinson's disease, only helps manage symptoms

Side Effects of SYNCAPONE 100MG TABLET (LEVODOPA 100MG+CARBIDOPA 25MG+ENTACAPONE 200MG)

COMMON SIDE EFFECTS

• Nausea
• Diarrhoea
• Dark urine (harmless colour change)
• Dizziness
• Involuntary movements (dyskinesia)

LESS COMMON SIDE EFFECTS

• Dry mouth
• Sleep disturbances or vivid dreams
• Constipation
• Headache
• Fatigue

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Fainting or severe dizziness on standing
• Hallucinations or confusion
• Uncontrollable muscle movements that worsen suddenly
• Signs of an allergic reaction such as rash, swelling, or difficulty breathing
• High fever with muscle stiffness and confusion (rare but serious reaction)

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use SYNCAPONE 100MG TABLET (LEVODOPA 100MG+CARBIDOPA 25MG+ENTACAPONE 200MG)

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually multiple times a day
• Can be taken with or without food, but a high-protein meal may reduce absorption, so try to keep meal timing consistent
• Swallow the tablet whole with water; do not crush unless your doctor says it is fine
• Do not stop suddenly without consulting your doctor, as this can worsen symptoms

IF YOU MISS A DOSE

• Take it as soon as you remember
• If it is almost time for the next dose, skip the missed one and continue your normal schedule
• Do not take a double dose to make up for a missed one
• If you miss doses often, discuss a reminder plan with your doctor

STORAGE

• Store at room temperature, away from direct heat, light and moisture
• Keep the medicine in its original strip or container
• Keep out of reach of children and pets
• Discard any expired or unused medicine safely, do not flush it down the drain

Safety Information and Precautions for SYNCAPONE 100MG TABLET (LEVODOPA 100MG+CARBIDOPA 25MG+ENTACAPONE 200MG)

This is a prescription-only medicine in India and should be used only under medical supervision.

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to levodopa, carbidopa, entacapone or any ingredient in the tablet
• Have narrow-angle glaucoma
• Have a history of certain skin cancers (melanoma) without medical clearance
• Are taking certain medicines for depression called non-selective MAO inhibitors

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have liver or kidney disease
• Have heart disease, including irregular heartbeat
• Have a history of stomach ulcers
• Have mental health conditions like depression, psychosis, or hallucinations
• Are pregnant, planning pregnancy, or breastfeeding

MEDICINES THAT CAN INTERACT

• Antidepressants, especially MAO inhibitors
• Antipsychotic medicines
• Iron supplements, which can reduce absorption
• Blood pressure medicines, as combined use may cause low blood pressure
• Other Parkinson's disease medicines

FREQUENTLY ASKED QUESTIONS

Can I drive after taking this medicine?

It may cause dizziness or sudden sleepiness, so avoid driving until you know how it affects you.

Will my urine or sweat change colour?

Yes, dark colouring of urine or sweat is a harmless and common effect of this medicine.

Can I stop this medicine once I feel better?

• No, stopping suddenly can worsen Parkinson's symptoms; always consult your doctor before making changes.
• Doctor ya pharmacist se salah lein.