Glibenclamide 5mg + Metformin 500mg

Glibenclamide 5mg + Metformin 500mg — Uses and Benefits

This medicine is used to manage type 2 diabetes mellitus, especially when diet, exercise and a single diabetes medicine are not enough to control blood sugar levels.

WHAT THIS MEDICINE IS USED FOR

• Controlling high blood sugar in type 2 diabetes
• Used when metformin alone does not control sugar levels adequately
• Helps lower risk of long-term diabetes complications when blood sugar is controlled

HOW IT WORKS

• Glibenclamide stimulates the pancreas to release more insulin
• Metformin decreases glucose production by the liver
• Metformin also improves how muscles and tissues use insulin
• Together they lower blood sugar through two different mechanisms

WHAT IT IS NOT USED FOR

• Not used for type 1 diabetes
• Not used for diabetic ketoacidosis
• Not a treatment for weight loss
• Not meant for occasional or as-needed use; it is a regular daily therapy

How to Use Glibenclamide 5mg + Metformin 500mg

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually with breakfast or the first main meal
• Swallow the tablet with water; do not crush or chew unless advised
• Do not skip meals after taking this medicine as it can cause low blood sugar
• Continue to follow diet and exercise advice given by your doctor
• Do not increase or decrease the dose on your own

IF YOU MISS A DOSE

• Take it as soon as you remember with food
• If it is almost time for your next dose, skip the missed one
• Do not take two doses together to make up for a missed one
• If you frequently miss doses, discuss a reminder plan with your doctor

STORAGE

• Store at room temperature, away from heat and direct sunlight
• Keep in a dry place, away from moisture
• Keep out of reach of children
• Do not use after the expiry date printed on the pack

Glibenclamide 5mg + Metformin 500mg — Side Effects

COMMON SIDE EFFECTS

• Nausea
• Diarrhoea
• Stomach upset
• Loss of appetite
• Metallic taste in mouth

LESS COMMON SIDE EFFECTS

• Headache
• Dizziness
• Skin rash
• Weight gain
• Mild low blood sugar episodes

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Severe hypoglycemia with confusion, sweating, shakiness, or loss of consciousness
• Signs of lactic acidosis such as unusual tiredness, muscle pain, difficulty breathing, stomach pain with vomiting
• Yellowing of skin or eyes (jaundice)
• Severe allergic reaction with swelling of face, lips or throat, or difficulty breathing
• Dark urine or pale stools

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

Glibenclamide 5mg + Metformin 500mg — Safety Information and Precautions

This is a prescription-only medicine in India and should be used only under medical supervision.

DO NOT TAKE THIS MEDICINE IF YOU

• Have type 1 diabetes or diabetic ketoacidosis
• Have severe kidney or liver disease
• Have a known allergy to glibenclamide, metformin, or sulfonylurea medicines
• Are having a serious infection, surgery, or severe dehydration

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Are pregnant, planning pregnancy, or breastfeeding
• Have heart, liver or kidney problems
• Drink alcohol regularly
• Are elderly, as risk of low blood sugar is higher
• Are scheduled for any surgery or imaging test using contrast dye

MEDICINES THAT CAN INTERACT

• Other diabetes medicines or insulin
• Steroids
• Diuretics (water pills)
• Certain antibiotics and antifungal medicines
• Blood thinners like warfarin
• Alcohol

FREQUENTLY ASKED QUESTIONS

Can I stop this medicine once my sugar is normal?

No, do not stop without consulting your doctor, as diabetes needs continuous management.

Can I drink alcohol while taking this medicine?

It is best to avoid alcohol as it increases the risk of low blood sugar and lactic acidosis.

Will this medicine cause low blood sugar?

• Yes, it can, especially if a meal is skipped or delayed, so always carry a sugar source with you.
• Doctor ya pharmacist se salah lein.