Methotrexate 5mg

Methotrexate 5mg — Uses and Benefits

Methotrexate is used to treat autoimmune and inflammatory conditions, and certain types of cancer, by controlling overactive immune activity or abnormal cell growth.

WHAT THIS MEDICINE IS USED FOR

• Rheumatoid arthritis and other autoimmune joint diseases
• Severe psoriasis not controlled by other treatments
• Certain types of cancer as part of chemotherapy
• Some other autoimmune conditions as advised by a specialist

HOW IT WORKS

• It blocks an enzyme needed for cell division, slowing down rapidly multiplying cells
• This reduces inflammation and immune overactivity in autoimmune diseases
• In cancer, it helps stop growth of cancer cells

WHAT IT IS NOT USED FOR

• It is not a painkiller and will not give immediate relief from joint pain
• It is not used for common infections or fever
• It is not suitable for use during pregnancy
• It should not be used without regular blood test monitoring

This medicine must only be taken exactly as prescribed, usually once a week, never daily unless specifically advised for certain cancer treatments.

How to Use Methotrexate 5mg

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually once a week on the same day each week, unless told otherwise for cancer treatment
• Swallow the tablet with a glass of water, with or without food
• Do not increase or change your dose without consulting your doctor
• Take folic acid supplements if advised, to reduce side effects
• Never take this medicine daily by mistake, as this can be dangerous

IF YOU MISS A DOSE

• Contact your doctor or pharmacist for guidance rather than doubling the next dose
• Do not take an extra dose to make up for a missed one
• Keep a note or reminder of your weekly dosing day to avoid missing doses

STORAGE

• Store at room temperature, away from direct sunlight and moisture
• Keep out of reach of children
• Do not use after the expiry date printed on the pack
• Dispose of unused medicine safely, do not flush down the toilet

Methotrexate 5mg — Side Effects

COMMON SIDE EFFECTS

• Nausea and loss of appetite
• Mouth ulcers
• Tiredness or weakness
• Mild hair thinning

LESS COMMON SIDE EFFECTS

• Diarrhoea or stomach upset
• Headache
• Dizziness
• Skin rash or increased sun sensitivity

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Yellowing of skin or eyes, dark urine (liver problems)
• Unusual bleeding, bruising, or signs of infection like fever and sore throat (blood problems)
• Severe breathlessness or persistent dry cough (lung problems)
• Severe mouth ulcers or vomiting blood
• Severe diarrhoea or black stools
• Signs of allergic reaction such as swelling of face, lips, or difficulty breathing

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

Methotrexate 5mg — Safety Information and Precautions

This is a prescription-only medicine in India and should never be taken without a doctor's supervision and regular blood monitoring.

DO NOT TAKE THIS MEDICINE IF YOU

• Are pregnant or planning pregnancy, or are breastfeeding
• Have severe liver or kidney disease
• Have a known allergy to methotrexate
• Have active serious infection
• Have significant blood disorders

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have any liver, kidney, or lung disease
• Drink alcohol regularly
• Are planning to father a child or become pregnant
• Are taking any other medicines, including over-the-counter drugs
• Have a weak immune system or recent infections

MEDICINES THAT CAN INTERACT

• NSAIDs like ibuprofen (increase toxicity risk)
• Certain antibiotics like trimethoprim
• Other medicines affecting the liver or bone marrow
• Alcohol, which increases liver risk
• Live vaccines, which should be avoided during treatment

FREQUENTLY ASKED QUESTIONS

Can I take this medicine daily?

No, it is usually taken once a week; taking it daily by mistake can cause serious harm.

Why do I need folic acid with this medicine?

Folic acid helps reduce common side effects like mouth ulcers and nausea caused by methotrexate.

Is it safe during pregnancy?

• No, it can harm the baby and should be avoided during pregnancy and while trying to conceive.
• Doctor ya pharmacist se salah lein.