Mirabegron (25mg) + Silodosin (8mg)

Mirabegron (25mg) + Silodosin (8mg) — Uses and Benefits

This medicine is prescribed for men who have both an overactive bladder and an enlarged prostate, a common condition causing urinary symptoms.

WHAT THIS MEDICINE IS USED FOR

• Treating frequent and urgent need to urinate
• Reducing episodes of urinary leakage (urge incontinence)
• Improving urine flow in men with an enlarged prostate
• Reducing night-time trips to the bathroom (nocturia)

HOW IT WORKS

• Mirabegron relaxes the bladder muscle, allowing it to hold more urine and reducing sudden urges
• Silodosin relaxes the muscles in the prostate and bladder neck, making it easier to pass urine
• Together they improve both bladder storage and urine flow

WHAT IT IS NOT USED FOR

• Not used for urinary tract infections
• Not used for kidney stones
• Not used for prostate cancer
• Not a treatment for erectile dysfunction
• Not recommended for use in women or children

How to Use Mirabegron (25mg) + Silodosin (8mg)

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually once a day
• Take after a meal, at the same time each day
• Swallow the tablet whole with water; do not crush or chew it
• Do not stop the medicine without consulting your doctor, even if symptoms improve

IF YOU MISS A DOSE

• Take it as soon as you remember on the same day
• If it is almost time for your next dose, skip the missed dose
• Do not take two doses together to make up for a missed one

STORAGE

• Store at room temperature, away from direct sunlight and moisture
• Keep in the original pack until it is time to take it
• Keep out of reach of children
• Do not use after the expiry date printed on the pack

Mirabegron (25mg) + Silodosin (8mg) — Side Effects

COMMON SIDE EFFECTS

• Dizziness
• Headache
• Dry mouth
• Abnormal or retrograde ejaculation
• Nasal congestion or runny nose

LESS COMMON SIDE EFFECTS

• Constipation or diarrhoea
• Nausea
• Fast heartbeat (palpitations)
• Low blood pressure on standing up
• Fatigue

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Fainting or severe dizziness
• Swelling of face, lips, tongue or throat (allergic reaction)
• Difficulty breathing
• Painful or prolonged erection (priapism)
• Very high blood pressure or irregular heartbeat
• Inability to pass urine at all

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

Mirabegron (25mg) + Silodosin (8mg) — Safety Information and Precautions

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to Mirabegron, Silodosin, or any other ingredient in this medicine
• Are a woman or a child (this medicine is meant for adult men)
• Have severe uncontrolled high blood pressure
• Have severe liver or kidney disease
• Are scheduled for cataract or other eye surgery soon

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have heart disease, irregular heartbeat, or high blood pressure
• Have liver or kidney problems
• Have a history of fainting or low blood pressure on standing
• Are taking medicines for erectile dysfunction or other prostate medicines
• Are planning any eye surgery in the near future

MEDICINES THAT CAN INTERACT

• Other alpha-blockers used for prostate or blood pressure problems
• Medicines that affect heart rhythm (QT-prolonging drugs)
• Strong antifungal or antibiotic medicines (like ketoconazole)
• Blood pressure lowering medicines
• Other overactive bladder medicines

FREQUENTLY ASKED QUESTIONS

Can this medicine be taken by women?

No, this combination is meant only for men with an enlarged prostate and overactive bladder symptoms.

Will this medicine affect my blood pressure suddenly?

It can cause a drop in blood pressure, especially on standing up quickly, so rise slowly from sitting or lying positions.

How long does it take to see improvement?

• Most men notice improvement in urinary symptoms within a few weeks, but it may take longer for full effect; do not stop the medicine without talking to your doctor.
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