Rifampicin 60 mg + Isoniazid 30 mg

Rifampicin 60 mg + Isoniazid 30 mg — Uses and Benefits

This combination medicine is mainly used to treat tuberculosis (TB), a bacterial infection that most commonly affects the lungs but can also affect other parts of the body.

WHAT THIS MEDICINE IS USED FOR

• Treatment of pulmonary (lung) tuberculosis
• Treatment of certain forms of extra-pulmonary tuberculosis, as advised by your doctor
• Used as part of a combination anti-TB treatment regimen, along with other medicines

HOW IT WORKS

• Rifampicin blocks an enzyme that TB bacteria need to make RNA, stopping their growth
• Isoniazid stops the bacteria from building their cell wall, killing the bacteria
• Together they act on different stages of bacterial growth, making treatment more effective and reducing chances of drug resistance

WHAT IT IS NOT USED FOR

• Not used for viral infections like cold, flu, or COVID-19
• Not used for ordinary bacterial infections such as urinary or throat infections
• Not a painkiller or fever medicine
• Should not be used alone for TB treatment without other prescribed anti-TB drugs

How to Use Rifampicin 60 mg + Isoniazid 30 mg

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually once daily
• Best taken on an empty stomach, at least 30 minutes before food, unless your doctor advises otherwise
• Swallow the tablet with a full glass of water; do not crush or chew unless advised
• Take it at the same time every day to maintain steady levels in the body
• Complete the full course of treatment even if you feel better; stopping early can cause the infection to return or become drug-resistant
• Do not skip doses, as irregular use increases risk of treatment failure

IF YOU MISS A DOSE

• Take the missed dose as soon as you remember on the same day
• If it is almost time for your next dose, skip the missed one and continue your normal schedule
• Do not take a double dose to make up for the missed one
• If you miss several doses, inform your doctor promptly

STORAGE

• Store at room temperature, away from direct sunlight and moisture
• Keep in the original container, tightly closed
• Keep out of reach of children
• Do not use after the expiry date printed on the pack

Rifampicin 60 mg + Isoniazid 30 mg — Side Effects

COMMON SIDE EFFECTS

• Nausea or vomiting
• Loss of appetite
• Stomach upset
• Reddish-orange discoloration of urine, sweat, or tears (harmless)

LESS COMMON SIDE EFFECTS

• Headache
• Dizziness
• Tingling or numbness in hands or feet
• Mild skin rash or itching

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Yellowing of skin or eyes, dark urine (signs of liver damage)
• Severe stomach pain with vomiting
• Unexplained bruising or bleeding
• Severe skin rash, blistering, or peeling
• Swelling of face, lips, or throat, or difficulty breathing (allergic reaction)
• Fever with chills or flu-like symptoms
• Persistent numbness, tingling, or weakness in limbs

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

Rifampicin 60 mg + Isoniazid 30 mg — Safety Information and Precautions

This is a prescription-only medicine in India and should be used only under the supervision of a qualified doctor.

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to rifampicin, isoniazid, or any related medicines
• Have severe active liver disease
• Had previous isoniazid-related liver damage or hepatitis

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have any liver or kidney problems
• Are pregnant, planning pregnancy, or breastfeeding
• Drink alcohol regularly
• Have diabetes or peripheral neuropathy (nerve problems)
• Are taking oral contraceptives, as this medicine can reduce their effectiveness
• Have a history of seizures or psychiatric illness

MEDICINES THAT CAN INTERACT

• Oral contraceptive pills (reduced effectiveness)
• Anticoagulants like warfarin
• Anti-HIV medicines (protease inhibitors)
• Diabetes medicines
• Anti-epileptic drugs like phenytoin
• Other medicines that affect the liver, including certain antifungals
• Alcohol, which increases risk of liver damage

FREQUENTLY ASKED QUESTIONS

Can I stop the medicine once I feel better?

No, you must complete the full course as advised by your doctor, otherwise TB can relapse or become drug-resistant.

Will my urine change color?

Yes, reddish-orange discoloration of urine, sweat, and tears is common and harmless with rifampicin.

Can I drink alcohol while taking this medicine?

• It is best to avoid alcohol as it increases the risk of liver damage during treatment.
• Doctor ya pharmacist se salah lein.