AMITONE PLUS Tablets

Uses and Benefits of AMITONE PLUS Tablets (CHLORDIAZEPOXIDE 5MG + AMITRIPTYLINE 12.5MG)

This composition is prescribed for the treatment of mixed anxiety and depressive symptoms, where a person experiences both low mood and anxiety together.

WHAT THIS MEDICINE IS USED FOR

• Anxiety associated with depression
• Sleep disturbance linked to anxiety or depression
• Nervous tension, restlessness, and irritability seen with depressive illness

HOW IT WORKS

• Chlordiazepoxide calms the nervous system by enhancing the activity of a natural chemical (GABA) that reduces anxiety
• Amitriptyline increases the levels of certain brain chemicals (serotonin and noradrenaline) that help regulate mood
• Together they relieve both the emotional and physical symptoms of combined anxiety-depression

WHAT IT IS NOT USED FOR

• Not used for simple sleeplessness without anxiety or depression
• Not used for everyday stress that does not need medical treatment
• Not a painkiller, though it may sometimes be used off-label for nerve-related pain under specialist advice
• Not meant for long-term or unsupervised use

Side Effects of AMITONE PLUS Tablets (CHLORDIAZEPOXIDE 5MG + AMITRIPTYLINE 12.5MG)

COMMON SIDE EFFECTS

• Drowsiness or sedation
• Dry mouth
• Dizziness
• Blurred vision
• Constipation
• Weight gain

LESS COMMON SIDE EFFECTS

• Low blood pressure on standing up
• Difficulty passing urine
• Confusion, especially in elderly people
• Skin rash
• Increased appetite

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Irregular heartbeat or palpitations
• Severe drowsiness or difficulty waking up
• Yellowing of skin or eyes (jaundice)
• Suicidal thoughts or worsening depression
• Seizures or fainting
• Severe allergic reaction (swelling of face/throat, breathing difficulty)

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use AMITONE PLUS Tablets (CHLORDIAZEPOXIDE 5MG + AMITRIPTYLINE 12.5MG)

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually with water
• Can be taken with or without food, unless your doctor says otherwise
• Try to take it at the same time(s) each day to maintain steady effect
• Do not stop suddenly without consulting your doctor, as this can cause withdrawal symptoms
• Avoid alcohol while taking this medicine
• Do not increase or decrease the dose on your own

IF YOU MISS A DOSE

• Take it as soon as you remember
• If it is almost time for your next dose, skip the missed one
• Do not take two doses together to make up for a missed one

STORAGE

• Store at room temperature, away from direct sunlight and moisture
• Keep out of reach of children
• Do not use after the expiry date printed on the pack
• Discard unused medicine safely, do not flush down the drain

Safety Information and Precautions for AMITONE PLUS Tablets (CHLORDIAZEPOXIDE 5MG + AMITRIPTYLINE 12.5MG)

This is a prescription-only medicine in India and should only be used under medical supervision.

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to chlordiazepoxide, amitriptyline, or any ingredient in the medicine
• Have had a recent heart attack
• Have severe liver disease
• Are in a state of acute alcohol or drug intoxication
• Are taking or have recently stopped MAO inhibitor medicines

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have heart disease, glaucoma, or urinary retention problems
• Have epilepsy or a history of seizures
• Have liver or kidney disease
• Are pregnant, planning pregnancy, or breastfeeding
• Are elderly, as you may be more sensitive to side effects
• Have a history of substance abuse or depression with suicidal thoughts

MEDICINES THAT CAN INTERACT

• Other sedatives, sleeping pills, or anti-anxiety medicines
• Alcohol
• MAO inhibitors and certain other antidepressants
• Blood pressure medicines
• Medicines affecting heart rhythm
• Antihistamines or other drugs causing drowsiness

FREQUENTLY ASKED QUESTIONS

Can I drive after taking this medicine?

No, it can cause drowsiness and slow reflexes, so avoid driving or operating machinery until you know how it affects you.

Is this medicine habit-forming?

Yes, chlordiazepoxide can cause dependence if used for a long time, so it should be taken only for the duration your doctor advises.

Can I stop taking it once I feel better?

• No, stopping suddenly can cause withdrawal or rebound symptoms; your doctor will guide you on tapering the dose safely.
• Doctor ya pharmacist se salah lein.