XYGREL-AS COMBIKIT

Uses and Benefits of XYGREL-AS COMBIKIT (Ticagrelor (90mg) + Aspirin (75mg))

This composition is mainly used to reduce the risk of heart attack, stroke, or death in people with acute coronary syndrome (such as heart attack or unstable angina) or those who have undergone a stent placement procedure.

WHAT THIS MEDICINE IS USED FOR

• Prevention of heart attack and stroke in people with a history of acute coronary syndrome
• Prevention of blood clots after angioplasty or stent placement
• Long-term protection of heart blood vessels in high-risk patients

HOW IT WORKS

• Ticagrelor blocks platelets from sticking together, reducing clot formation
• Aspirin also prevents platelets from clumping, working through a different pathway
• Together they provide stronger protection against clot-related heart events than either alone

WHAT IT IS NOT USED FOR

• Not used for routine pain relief or fever
• Not a treatment for active bleeding or stroke caused by bleeding
• Not meant for general prevention in people without heart disease risk factors
• Not a substitute for other prescribed heart medicines like statins or blood pressure drugs

Side Effects of XYGREL-AS COMBIKIT (Ticagrelor (90mg) + Aspirin (75mg))

COMMON SIDE EFFECTS

• Easy bruising
• Nosebleeds
• Minor bleeding from gums while brushing
• Shortness of breath
• Stomach upset or indigestion

LESS COMMON SIDE EFFECTS

• Dizziness or headache
• Diarrhoea or nausea
• Skin rash or itching
• Low blood pressure

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Blood in vomit, stool, or urine
• Black or tarry stools
• Coughing up blood
• Severe or uncontrolled bleeding from a cut or wound
• Sudden severe headache, confusion, or difficulty speaking (signs of bleeding in the brain)
• Severe allergic reaction with swelling of face, lips, or throat, and difficulty breathing
• Unusual tiredness with pale skin (signs of low blood counts)

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use XYGREL-AS COMBIKIT (Ticagrelor (90mg) + Aspirin (75mg))

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually with or without food
• Swallow the tablet with a glass of water; do not crush or chew unless advised
• Take it at the same time each day to maintain consistent blood levels
• Do not stop taking this medicine suddenly without consulting your doctor, especially if you have a stent, as this can increase risk of clot formation
• Continue taking it for as long as your doctor recommends, even if you feel well

IF YOU MISS A DOSE

• Take it as soon as you remember on the same day
• If it is almost time for your next dose, skip the missed dose and continue your regular schedule
• Do not take a double dose to make up for a missed one
• If you miss doses often, set reminders or inform your doctor

STORAGE

• Store at room temperature, away from direct sunlight and moisture
• Keep the tablets in their original strip or container until use
• Keep out of reach of children
• Do not use beyond the expiry date printed on the pack

Safety Information and Precautions for XYGREL-AS COMBIKIT (Ticagrelor (90mg) + Aspirin (75mg))

This is a prescription-only medicine in India and should be used strictly under a doctor's supervision.

DO NOT TAKE THIS MEDICINE IF YOU

• Are actively bleeding, such as a stomach ulcer or bleeding in the brain
• Have severe liver disease
• Have a known allergy to ticagrelor, aspirin, or other NSAIDs
• Have a history of bleeding disorders

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have had a recent surgery or plan to undergo any surgery or dental procedure
• Have kidney or liver problems
• Have asthma or history of stomach ulcers
• Are pregnant, planning pregnancy, or breastfeeding
• Have a history of gout or bleeding tendency

MEDICINES THAT CAN INTERACT

• Other blood thinners like warfarin or heparin
• NSAID painkillers such as ibuprofen or diclofenac
• Certain antifungal or HIV medicines
• Strong CYP3A4 inhibitors or inducers (such as certain antibiotics or seizure medicines)
• Herbal supplements that affect bleeding, like ginkgo biloba

FREQUENTLY ASKED QUESTIONS

Can I stop this medicine on my own once I feel better?

No, stopping suddenly, especially after a stent, can increase the risk of a serious clot; always consult your doctor first.

Can I take painkillers along with this medicine?

Avoid NSAID painkillers unless your doctor approves, as they can increase bleeding risk; paracetamol is usually safer.

Will this medicine make me bleed more easily during injury?

• Yes, it reduces blood clotting, so cuts may bleed longer and bruising may occur more easily; inform any doctor or dentist that you are on this medicine.
• Doctor ya pharmacist se salah lein.