ZORYL MP 1 FORTE TABLET

Uses and Benefits of ZORYL MP 1 FORTE TABLET (GLIMEPIRIDE 1 MG + METFORMIN 1000 MG + PIOGLITAZONE 15 MG)

This medicine combination is used to manage type 2 diabetes mellitus, especially when diet, exercise and a single diabetes medicine are not enough to control blood sugar.

WHAT THIS MEDICINE IS USED FOR

• Controlling high blood sugar levels in type 2 diabetes
• Used when metformin alone does not give adequate control
• Helps reduce the risk of long-term diabetes complications when blood sugar is well controlled

HOW IT WORKS

• Glimepiride helps the pancreas release more insulin
• Metformin reduces the amount of sugar produced by the liver and improves the body's response to insulin
• Pioglitazone makes the body's cells more sensitive to insulin, helping muscle and fat use sugar better

WHAT IT IS NOT USED FOR

• Not used for type 1 diabetes
• Not used for diabetic ketoacidosis, a medical emergency
• Not a substitute for diet and lifestyle changes advised by your doctor
• Not meant for occasional or as-needed use; it is a regular daily treatment

Side Effects of ZORYL MP 1 FORTE TABLET (GLIMEPIRIDE 1 MG + METFORMIN 1000 MG + PIOGLITAZONE 15 MG)

COMMON SIDE EFFECTS

• Nausea or stomach upset
• Diarrhoea
• Loss of appetite
• Weight gain
• Mild low blood sugar (hunger, sweating, shakiness)

LESS COMMON SIDE EFFECTS

• Headache
• Swelling in feet or ankles
• Metallic taste in mouth
• Dizziness

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Severe low blood sugar with confusion, seizures or loss of consciousness
• Signs of lactic acidosis: unusual tiredness, muscle pain, difficulty breathing, stomach pain
• Yellowing of skin or eyes, dark urine (liver problems)
• Sudden weight gain, shortness of breath, or chest pain (possible heart or fluid-related problem)
• Signs of an allergic reaction: rash, swelling of face or throat, difficulty breathing
• Bone fractures with long-term use

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use ZORYL MP 1 FORTE TABLET (GLIMEPIRIDE 1 MG + METFORMIN 1000 MG + PIOGLITAZONE 15 MG)

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually with the first main meal of the day
• Swallow the tablet whole with water; do not crush or chew unless advised
• Do not skip meals after taking this medicine, as it can cause low blood sugar
• Continue regular blood sugar monitoring as advised by your doctor
• Do not stop the medicine suddenly without consulting your doctor

IF YOU MISS A DOSE

• Take it as soon as you remember with food
• If it is almost time for your next dose, skip the missed dose
• Do not take two doses together to make up for a missed one

STORAGE

• Store at room temperature, away from direct sunlight and moisture
• Keep the strip in its original packaging
• Keep out of reach of children
• Do not use after the expiry date printed on the pack

Safety Information and Precautions for ZORYL MP 1 FORTE TABLET (GLIMEPIRIDE 1 MG + METFORMIN 1000 MG + PIOGLITAZONE 15 MG)

This is a prescription-only medicine in India and should be used only under the supervision of a registered doctor.

DO NOT TAKE THIS MEDICINE IF YOU

• Have type 1 diabetes or diabetic ketoacidosis
• Have severe kidney or liver disease
• Have heart failure or a history of bladder cancer
• Are pregnant or breastfeeding
• Are allergic to any of the three ingredients

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have any heart, liver or kidney condition
• Drink alcohol regularly
• Are scheduled for surgery or an X-ray with contrast dye
• Have a history of low blood sugar episodes
• Have osteoporosis or are at risk of fractures

MEDICINES THAT CAN INTERACT

• Other diabetes medicines or insulin
• Steroids and certain blood pressure medicines
• Alcohol, which increases risk of low blood sugar and lactic acidosis
• Certain antibiotics and pain relievers (NSAIDs)
• Contrast dye used in imaging tests

FREQUENTLY ASKED QUESTIONS

Can I drink alcohol while taking this medicine?

It is best to avoid alcohol as it can increase the risk of low blood sugar and a rare but serious condition called lactic acidosis.

Will this medicine cause weight gain?

Some weight gain and fluid retention can occur with this combination; discuss any noticeable weight change with your doctor.

How long do I need to take this medicine?

• Type 2 diabetes usually needs long-term treatment, so continue taking it as long as your doctor recommends, even if you feel well.
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