ISTAMET-G IR 50/500/2MG TABLET

Uses and Benefits of ISTAMET-G IR 50/500/2MG TABLET (Glimepiride 2mg + Sitagliptin 50mg + Metformin 500mg)

This medicine is used to manage blood sugar levels in adults with type 2 diabetes mellitus.

WHAT THIS MEDICINE IS USED FOR

• Controlling high blood sugar levels in type 2 diabetes
• Used when diet, exercise, and a single diabetes medicine are not enough to control sugar levels
• Often prescribed as part of a combination treatment plan

HOW IT WORKS

• Glimepiride helps the pancreas release more insulin
• Sitagliptin helps the body produce more insulin after meals and reduces sugar release from the liver
• Metformin reduces sugar production by the liver and improves the body's response to insulin

WHAT IT IS NOT USED FOR

• Not used for type 1 diabetes
• Not used for diabetic ketoacidosis, a serious emergency condition
• Not a substitute for insulin when insulin is specifically required
• Not used for weight loss or any purpose other than blood sugar control

Side Effects of ISTAMET-G IR 50/500/2MG TABLET (Glimepiride 2mg + Sitagliptin 50mg + Metformin 500mg)

COMMON SIDE EFFECTS

• Nausea
• Diarrhoea
• Stomach upset
• Loss of appetite
• Metallic taste in mouth

LESS COMMON SIDE EFFECTS

• Headache
• Dizziness
• Skin rash
• Mild weight gain
• Low blood sugar (hypoglycemia), especially if meals are skipped

SERIOUS SIDE EFFECTS — STOP AND SEE A DOCTOR IMMEDIATELY

• Signs of severe low blood sugar such as excessive sweating, confusion, shakiness, or fainting
• Signs of lactic acidosis such as severe weakness, muscle pain, trouble breathing, unusual tiredness
• Severe stomach pain that may spread to the back, with or without vomiting (possible pancreatitis)
• Yellowing of eyes or skin, dark urine (liver problem)
• Severe allergic reaction with swelling of face, lips, throat, or difficulty breathing
• Joint pain that is severe and persistent

This is not a complete list. Report any unusual or persistent symptom to your doctor or pharmacist.

How to Use ISTAMET-G IR 50/500/2MG TABLET (Glimepiride 2mg + Sitagliptin 50mg + Metformin 500mg)

HOW TO TAKE IT

• Take exactly as prescribed by your doctor, usually with breakfast or the first main meal
• Swallow the tablet whole with water; do not crush or chew
• Do not skip meals after taking this medicine, as it can cause low blood sugar
• Continue taking it regularly even if you feel well
• Do not change the dose on your own

IF YOU MISS A DOSE

• Take it as soon as you remember
• If it is almost time for the next dose, skip the missed one
• Do not take two doses together to make up for a missed one
• If you often forget doses, ask your doctor about setting reminders

STORAGE

• Store at room temperature, away from direct sunlight and moisture
• Keep in the original pack until it is time to take it
• Keep out of reach of children
• Do not use after the expiry date printed on the pack

Safety Information and Precautions for ISTAMET-G IR 50/500/2MG TABLET (Glimepiride 2mg + Sitagliptin 50mg + Metformin 500mg)

This medicine is available only with a valid doctor's prescription in India.

DO NOT TAKE THIS MEDICINE IF YOU

• Are allergic to glimepiride, sitagliptin, metformin, or any sulfonylurea drug
• Have type 1 diabetes or diabetic ketoacidosis
• Have severe kidney or liver disease
• Have a severe infection, injury, or are about to undergo surgery
• Are pregnant or breastfeeding, unless advised by your doctor

TELL YOUR DOCTOR BEFORE STARTING IF YOU

• Have any history of kidney, liver, heart, or pancreas problems
• Drink alcohol regularly
• Are scheduled for an X-ray or scan involving contrast dye
• Have a history of low blood sugar episodes
• Are elderly or have poor nutrition

MEDICINES THAT CAN INTERACT

• Other diabetes medicines or insulin
• Steroids
• Diuretics (water pills)
• Certain antibiotics and antifungal medicines
• Blood thinners
• Alcohol

Always share your full list of medicines and supplements with your doctor or pharmacist.

FREQUENTLY ASKED QUESTIONS

Can I stop this medicine once my sugar is controlled?

No, do not stop without consulting your doctor, as diabetes needs long-term management.

Can I drink alcohol while on this medicine?

Alcohol should be avoided or limited, as it can increase the risk of low blood sugar and other complications.

Will this medicine cause weight gain?

• Some weight gain may occur due to glimepiride, but metformin and sitagliptin usually have a neutral or minimal effect on weight.
• Doctor ya pharmacist se salah lein.